https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50139 Wed 05 Jul 2023 12:54:49 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48116 Wed 01 Mar 2023 13:27:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27063 2000 trait-associated genetic variants. Because most of these variants have individually small effects on disease risk, successful gene discovery efforts have required large sample sizes (involving thousands, tens, or hundreds of thousands of cases and controls) to achieve sufficient study power. Amassing such sample sizes has depended on international collaboration on a scale never seen before in human genetics or even in clinical research. Disease-specific consortia bringing together many individual sites and collaborators have now evolved for many major diseases. Each consortium has faced with ≥2 fundamental questions: how to assemble a study sample of sufficient size, homogeneity, and phenotypic quality and how to retain and analyze, sometimes repeatedly over several years, biological samples from enrolled subjects.]]> Thu 10 Sep 2020 18:07:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20950 Sat 24 Mar 2018 08:06:07 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48737 Fri 31 Mar 2023 16:23:23 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46168 Fri 11 Nov 2022 19:54:47 AEDT ]]>